office location:110 of Li Hua Lou
E-mail: huai_zhang@sina.com
Research Interests:modification and application of enzymes, synthetic biology, genetic engineering

Jun. 2005-Present University of Science and Technology Beijing
Sep. 2001-Jun. 2005 Beijing University of Chemical Technology, Ph.D.
Sep. 1998-Jun. 2001 Beijing University of Chemical Technology, Master
Sep. 1994-Jun. 1998 Beijing University of Chemical Technology, Bachelor

Scientific research achievements

We have developed the first L-dopa production route in the world that can be used in large-scale industrial production based on p-hydroxyphenylacetate 3-hydroxylase (PHAH) from Escherichia coli. The recombinant E.coli can product 40-50g/L L-dopa within 40 hours.
Method for improving production of L-phenylalanine through L-phenylalanine genetically engineered bacteria. CN201310432381.6

Enrollment plan


Representative papers

1. ZhangHuai, Yu Litao. Knockout of ptsG Gene of Escherichia coli w3110 and Its Impact on Production of Phenylalanine. Biotechnology Bulletin, 2010, 11: 177-181
2. H Zhang, QP Yuan, YP Zhu, RY Ma. Expression and preparation of recombinant hepcidin in Escherichia coli. Protein Expression and Purification, 2005, 41(2): 409-416
3.QP Yuan, H Zhang, ZM Qian and XJ Yang. Pilot-plant production of xylo-oligosaccharides from corncob by steaming, enzymatic hydrolysis and nanofiltration. Journal of Chemical Technology and Biotechnology, 2004, 79: 1073-1079

Postgraduate training


  • School of Chemistry and Biological Engineering, USTB
  • 30 Xueyuan Road, Haidian District, Beijing,100083