ZHANG Huai

Lecturer
office location:110 of Li Hua Lou
E-mail: huai_zhang@sina.com
Research Interests:modification and application of enzymes, synthetic biology, genetic engineering
Resume

Jun. 2005-Present University of Science and Technology Beijing
Sep. 2001-Jun. 2005 Beijing University of Chemical Technology, Ph.D.
Sep. 1998-Jun. 2001 Beijing University of Chemical Technology, Master
Sep. 1994-Jun. 1998 Beijing University of Chemical Technology, Bachelor

Scientific research achievements

We have developed the first L-dopa production route in the world that can be used in large-scale industrial production based on p-hydroxyphenylacetate 3-hydroxylase (PHAH) from Escherichia coli. The recombinant E.coli can product 40-50g/L L-dopa within 40 hours.
Patents:
Method for improving production of L-phenylalanine through L-phenylalanine genetically engineered bacteria. CN201310432381.6

Enrollment plan

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Representative papers

1. ZhangHuai, Yu Litao. Knockout of ptsG Gene of Escherichia coli w3110 and Its Impact on Production of Phenylalanine. Biotechnology Bulletin, 2010, 11: 177-181
2. H Zhang, QP Yuan, YP Zhu, RY Ma. Expression and preparation of recombinant hepcidin in Escherichia coli. Protein Expression and Purification, 2005, 41(2): 409-416
3.QP Yuan, H Zhang, ZM Qian and XJ Yang. Pilot-plant production of xylo-oligosaccharides from corncob by steaming, enzymatic hydrolysis and nanofiltration. Journal of Chemical Technology and Biotechnology, 2004, 79: 1073-1079

Postgraduate training

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  • School of Chemistry and Biological Engineering, USTB
  • 30 Xueyuan Road, Haidian District, Beijing,100083