LIU Liqin

Associate professor
office location:113 Physics and chemistry building
E-mail:liuliqin@ustb.edu.cn
Research Interests:Research on Tumor Diagnostic Drugs

Research on Targeted Therapeutic Drugs

Research on nano-drug carriers
Resume

Resume:
1、2012.07-2014.02:School of Pharmacy, University of New Mexico, USA, Post-doctor
2、2006.05 -----------:School of Chemistry and Biological engineering, University of Science and Technology Beijing, Associate professor
3、2003.09-2006.05:Peking Union Medical College Hospital, Peking Union Medical University of China, Post-doctor
4、2000.09-2003.09:Doctor of Science, Beijing Normal University
5、1997.09-2000.07:Master of Science, Northeast Forestry University
6、1993.09-1997.07:Bachelor of Science, Northeast Forestry University
Social Appointments:Peer Reviewer of J Radioanal Nucl Chem

Scientific research achievements

Awards:
(1)2010.09: “Marino Nicolini Prize”, the 8th International Symposium on TECHNETIUM and OTHER RADIOMETALS in CHEMISTRY and MEDICINE, Bressanone (Bolzano), Italy.
(2)2011.04: “Second prize”, the first teaching basic skills competition of young teachers in School of Chemistry and Biological engineering.
(3)2012.09: “Advanced Worker”, University of Science and Technology Beijing.
Undergraduate courses:《Developmental biology》、《Biochemical and Drug Analysis》

Enrollment plan

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Representative papers

Research project:
1、National Natural Science Youth Fund “The study on antitumor activity of targeted delivery HIF-1 α siRNA by silica nanoparticle-supported folate receptor targeted lipid”, 81301319, 230 thousand yuan, 2014. 01- 2016.12, Person in charge.
2、Fundamental research funds for the central universities “Study on novel nucleic acid molecular probes for early diagnosis of tumors”, FRF-BR-12-017, 100 thousand yuan, 2012.7-2014.7, Person in charge.
3、Sino-Russian International Cooperation Project “Study on the vaccine of prevention and immunotherapy and its new adjuvant enhancing function”, 2008AR, 300 thousand yuan, 2008.10—2011.10, Person in charge.
4、Fundamental research funds for the central universities “Study on Molecular Probes for Diagnosis of Tumor Hypoxia”, FRF-BR-09-006A, 100 thousand yuan, 2009.12-2011.12, Person in charge.
Selected publications:
[1] Liqin Liu, Jingli Xu, Jianquan Yang, Changjian Feng, Yubin Miao*. Metastatic melanoma imaging using a novel Tc-99m-labeled lactam-cyclized alpha-MSH peptide. Bioorganic & Medicinal Chemistry Letters, 2017, 27(22): 4952-4955.
[2] Liqin Liu, Jingli Xu, Jianquan Yang, Changjian Feng, Yubin Miao*. Imaging human melanoma using a novel Tc-99m-labeled lactam bridge-cyclized alpha-MSH peptide. Bioorganic & Medicinal Chemistry Letters, 2016, 26(19): 4724-4728.
[3] Liqin Liu, Yubin Miao*. Evaluationof a Novel Tc-99m-Labeled HYNIC-Conjugated Lactam Bridge-Cyclized Alpha-MSH Peptide for Human Melanoma Imaging. J Label Compd Radiopharm, 2015, 58: S75.
[4] Liqin Liu *, Zhuo Wang, Lili Chen. Synthesis and biodistribution of novel 99mTc labeled chitosan modified metronidazole analogs as a potential probe for tumor hypoxia imaging. J Label Compd Radiopharm, 2015, 58: S354.
[5]Liqin Liu*, Manchen Zhao, Zhuo Wang, Yuanyan Qin, Xuebin Wang. Synthesis and biological evaluation of novel technetium-99m labeled HYNIC-D-glucose as a potential tumor imaging agent. J Radioanal Nucl Chem, 2014, 301(4): 731–737.
[6]Liqin Liu*, Manchen Zhao, Zhuo Wang, Yuanyan Qin, Xuebin Wang. Synthesis and biodistribution of 99mTc-HYNIC-DG as a novel potential tumor imaging agent. Nuclear Medicine and Biology, 2014, 41(7): 623.
[7]Liqin Liu, Yubin Miao*. Metastatic melanoma targeting property of a novel Tc-99m-labeled HYNIC-conjugated lactam bridge-cyclized alpha-MSH peptide. Nuclear Medicine and Biology. 2014, 41(7): 622.
[8]Liqin Liu*, Junwei Wang, Yaqian Wei, Manchen Zhao, Lirui Liu, Xuebin Wang. Synthesis and biodistribution of 99mTcN-thymidine dithiocarbamate as a potential tumor imaging agent. J Label Compd Radiopharm, 2013, 56: S347.
[9]Jianquan Yang, Liqin Liu, Yubin Miao*. Effects of the Arg-Pro and Gly-Gly-Nle Moieties on Melanocortin-1 Receptor Binding Affinities of α-MSH Peptides. ACS Medicinal Chemistry Letters 2013, 4(10): 1000-1004.
[10]Liqin Liu*, Junwei Wang, Yaqian Wei, Manchen Zhao, Lirui Liu, Xuebin Wang. Synthesis and biodistribution of a novel 99mTc complex of HYNIC-Conjugated thymidine as a potential tumor imaging agent. J Label Compd Radiopharm, 2013, 56: S348.
[11]Liqin Liu*, Guangrong Zhong, Yaqian Wei, Min Zhang, Xuebin Wang. Synthesis and biological evaluation of a novel 99mTc complex of HYNIC-conjugated aminomethylenediphos-phonate as a potential bone imaging agent. J Radioanal Nucl Chem, 2011, 288(2): 467-473.
[12]Liqin Liu*, Min Zhang, Guangrong Zhong, Xuebin Wang. Synthesis and biodistribution of a novel 99mTc complex of HYNIC-conjugated metronidazole as a potential tumor hypoxia imaging agent. J Radioanal Nucl Chem, 2011, 287(3): 847-852.

Postgraduate training

Recruiting scheme:
Two Master's students are enrolled annually.

  • School of Chemistry and Biological Engineering, USTB
  • 30 Xueyuan Road, Haidian District, Beijing,100083